Fertility Research & Clinical Excellence

Fertility ResearchResearch to Preserve Oocytes | Egg Freezing

ACRM, in collaboration with Gwinnett Women's Pavillion of Gwinnett Medical Center,  received a substantial research grant from Gerald J. and Dorothy R. Friedman Foundation for Medical Research to aid in egg freezing clinical studies.

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A prospective, randomized clinical trial comparing the effect of metformin on pregnancy outcomes in women undergoing in vitro fertilization (IVF)

Metformin is a medication traditionally used in diabetic patients to improve insulin sensitivity. Its applications have extended far beyond that limited patient population in recent years. Metformin use in in vitro fertilization (IVF) patients with polycystic ovary syndrome (PCOS) is now a common practice. Some studies have demonstrated higher clinical pregnancy rates when the medication is utilized. Others have shown no benefits in pregnancy or live birth rates but have demonstrated a decreased incidence of ovarian hyperstimulation syndrome. However, the effects of empiric metformin use by non-PCOS patients undergoing IVF have not been studied in a randomized fashion.

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IPSO Trial – Impact of Parental Support on Pregnancy Outcomes

ACRM is currently recruiting healthy women undergoing In Vitro Fertilization (IVF) between the ages of 35 to 42 years to participate in a randomized, study. The purpose of the study is to determine whether PGS - testing of embryos created during IVF for chromosome abnormalities, prior to transfer to the uterus - improves pregnancy and implantation rates in patients when compared to patients whose embryos are not tested. PGS will be conducted using 24 Chromosome Aneuploidy Screening with Parental SupportTM from Gene Security Network.

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Additional Studies Currently Underway at ACRM

1. Timing of Luteal Phase Support in IVF and Pregnancy Outcomes -- a National Survey [Fogle & Toner]

2. Relationship between serum Progesterone levels and Pregnancy Outcomes in IVF cycles using vaginal Progesterone for Luteal Support [Toner]

3. Effect of Route of Progesterone administration on Pregnancy Rates in various types of Assisted Reproduction [Toner].

4. Impact of 24 Chromosome Aneuploidy Screening on Implantation and Pregnancy Rates in IVF [GSN; Toner].

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Publications & Presentations

View the list of publications produced by Atlanta Center for Reproductive Medicine.

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